
Sylvia Jablonski, Defiance ETFs
The First Autism Impact ETF — and 100% of Profits Go to the Cause
Sylvia Jablonski is the CEO of Defiance ETFs — a firm that's grown from a handful of products in 2018 to over $13 billion in AUM across 80-plus ETFs, with launches happening on a weekly cadence. In this return appearance on Behind the Ticker, Sylvia walks through the firm's most personal product yet and the SpaceX launch on deck.
The Defiance Autism Impact ETF (ticker ASD) launched on June 2nd, 2026, as the first ETF of its kind. The fund is built around the full value chain serving the autism community — drug development, genetic testing, behavioral therapies, educational platforms, assistive technology, digital health — and Defiance is donating 100% of net advisory profits to autism causes for the first two years, no less than 50% thereafter. Sylvia talks about the deeply personal story behind the fund, the investment case for a sector where one in 31 children is now diagnosed and the lifetime cost of care runs into the millions, and why institutional allocators are increasingly asking for products with a cause structurally built in.
The conversation then shifts to SPCU — the firm's 2X long SpaceX ETF, set to launch alongside what may be the largest IPO in history. Sylvia covers how Defiance has been building space exposure for years across single-name, thematic, and basket products (UFOX, SPCL, JEDI, XOVL), why the space economy has gone from niche theme to mainstream so quickly, and how Defiance is positioning across an increasingly crowded category.
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