Sylvia Jablonski, Defiance ETFs
The First Autism Impact ETF — and 100% of Profits Go to the Cause
Sylvia Jablonski is the CEO and Chief Investment Officer of Defiance ETFs. When she first joined Behind the Ticker, Defiance was a small, scrappy thematic shop. Today the firm runs more than 13 billion dollars across 80-plus ETFs and launches new products almost every week. She returns to talk through two launches that say a lot about where the firm is headed: the first autism impact ETF ever brought to market, and a 2X leveraged play on what may become the biggest IPO in history.
On this episode, Sylvia sits down with Brad to get into the personal story behind the autism fund, why allocators are asking for products with a cause built into the structure, and how a firm growing this fast decides what to launch next.
The First Autism Impact ETF
The Defiance Autism Impact ETF (ASD) launched in early June 2026 as the first fund of its kind. The story behind it is personal. Defiance founder Matt Bielski and his wife have a child on the autism spectrum, and the fund is the institutional expression of everything they have learned navigating diagnosis, therapies, and the financial realities that come with care.
ASD covers the full ecosystem serving the autism community: behavioral health, diagnostics, educational platforms, biotech, and assistive technology. The structure is the part that stops people. Defiance is donating 100 percent of net advisory profits to autism causes for the first two years, and no less than 50 percent thereafter. The cause is not a marketing layer on top of the fund. It is wired into how the product is built.
The Investment Case
The numbers behind the theme are hard to ignore. One in 31 children is now diagnosed with autism. There are no FDA-approved treatments for the core symptoms. And the projected lifetime cost of care runs into the millions per family. Rising prevalence against a deep unmet need is the kind of demand curve that does not reverse on a market cycle.
Sylvia makes the point that this is no longer a niche conversation. Institutional allocators are increasingly asking for products that pair a real investment case with a cause structurally built in, and ASD was designed to sit squarely in that demand.
A 2X Bet on SpaceX
The conversation then turns to SPCU, the firm's 2X long SpaceX ETF, which launched this month alongside what may be the largest IPO in history. Sylvia explains why Defiance has been building space economy exposure for years rather than rushing in on the IPO headline, and what makes the commercial case for SpaceX genuinely compelling beyond the Elon Musk factor.
Defiance now offers one of the most complete suites of space-themed products on the market, spanning single-name, thematic, and basket structures. SPCU is the leveraged expression of a theme the firm has been laying groundwork on for a long time.
Building at Speed
Underneath both launches is a question Brad keeps coming back to: how does a firm launch this many products this quickly and still pick well? Sylvia is candid about the cadence. Defiance launches nearly every week, but the funds that matter are the ones built around a real thesis and a real audience, not just a clever ticker. ASD and SPCU are both examples of that, very different products that each answer a specific demand the firm saw before the rest of the market did.
Key Takeaways
- ASD is the first autism impact ETF, covering behavioral health, diagnostics, education, biotech, and assistive technology, with 100 percent of net advisory profits donated to autism causes for the first two years and no less than 50 percent after.
- The investment case rests on structural demand: one in 31 children diagnosed, no FDA-approved treatments for core symptoms, and lifetime care costs in the millions.
- SPCU is a 2X long SpaceX ETF launched ahead of a potentially record-setting IPO, and it sits inside a broader Defiance space suite years in the making.
- Defiance has scaled to more than 13 billion dollars across 80-plus ETFs while launching at a near-weekly cadence, with a focus on funds built around a genuine thesis.
Listen to the full conversation on Spotify, Apple Podcasts, or YouTube.
Full Transcript
3,937 wordsMachine transcribed from Brad Roth's conversation with Sylvia Jablonski, Defiance ETFs, with speakers identified automatically. Timestamps link to that moment on YouTube. Lightly cleaned, otherwise unedited.
Welcome to Behind the Ticker, the podcast where we go beyond the symbol and into the strategy. I'm Brad Roth, founder and chief investment officer at Thor Funds. And in each episode, I sit down with ETF managers, CIOs, and industry leaders to break down how these funds are actually built, how they behave in real markets, and how advisors use them in real portfolios. Most people just see a ticker symbol, but we know much more goes on behind the ticker.
Hey, Sylvia, welcome back to the show. Thanks for having me, Brad. Great to be here.
So why don't we just take a minute? We have many more listeners and you have many more funds now since the last time we talked. So can you give everybody a quick refresher, maybe on your background and the journey that led you to become the CEO of Defiance?
Yeah, sure. So Defiance was launched in 2018 and the original founder of the company was Matt Belsky. A little bit of history. We worked together at Direction ETFs before that. So my career has been very much in ETFs. I spent some time on an equity derivatives Delta One desk. And then from there, I joined Direction in 2009 and Defiance in 2020. So I've very much grown up in ETFs, levered numbers, ETFs, thematic ETFs, and all of these things. And we were talking a little bit off camera, but the last time we spoke, I think we had a handful of products. So where we sit now is we have 80 plus funds. We're $13 billion in AUM. And the funds range from thematic ETFs, single name leverage ETFs, and income generating ETF products. And so, yeah, super happy to be here.
Read the full transcript (40 more sections)Collapse transcript
And thanks for having us. Sure. So why don't we just talk a little bit more about Defiance? As you mentioned, the firm launched in 2018, you've crossed $13 billion in assets. So for listeners who know some of your individual tickers, but might not know like the full story, what is the kind of philosophy at Defiance? And what is the product mix look like today? And as you've mentioned, it's
Changed so much. Yeah, so I would say that we've been pretty consistent with our theme, right? We try to be first to market with disruptive, new, innovative, disruptive technologies, or just, really new ideas and things that don't exist in the market that investors are very much talking about and looking for access to. So, a great example is the quantum ETF that came to the market in 2018. It was the first of its kind. And, kind of lo and behold, it takes some time for disruptive technologies to become commercial opportunities, right? And so, we like to be ahead of the curve with some of the themes and some of the products that we come to market with. And on the single name leverage stocks, there's just been this massive
Amount of growth in single name levered ETFs. You see billions of dollars pouring into some of these names. And a great example of that is like, we just had a launch a couple of weeks ago on a 2X Poet and the tickers P-O-E-L. that's a name that was not really well known a year ago. And this year, investors were buzzing about it. And we noticed it. So, we put it into the market. And that gathered, $100 million of assets, like, rather quickly and kept going up from there. So, we just try to be, again, ahead of the curve, bringing to the market the products that retail investors, hedge funds, institutional investors are really looking to trade and trying
To innovate and keep the product lineup relevant. I'm kind of curious what that process looks like, inside the walls of defiance, you've been right on a lot of themes. And what is the process like, behind closed doors when the team's deciding, what themes or single stock names are worth building around, what's not. And you guys have to move fast. So, I'm sure, there's not a lot of, the Western Pennsylvania is going to come out of me, the him hauling around, deciding what to do. You got to move fast. So, what's that process look like?
I think you answered the question actually really well with it, like, just with your intro there. There is no hem hawing at all, right? And I think that this year, we see, we see the, the speed, the veracity, the volume of ETF filings and launches from all issuers. So, it's very much a competitive world amongst us issuers out there in the market. When we have a good idea, we obviously think things through and we do all of the due diligence and the research and the, correct type of R&D prior to building an ETF. We're working with an index provider to build an ETF in some cases, but it's very much doing that quickly and efficiently and trying to gain
Some first mover advantage in some cases. Obviously, with the thematic funds, it takes a little bit more time to actually craft an idea. But, we just try to think about the different innovations and trends out there. for example, AI was a big thing, right? AI is a huge thing. It's the biggest topic in the market and the chat GPT moment really opened that up. And so, when that happened, there was a lot of money that just poured into the semiconductor ETFs or just Nvidia stock. And then companies like ours start looking at it and saying like, okay, so the AI trade is pretty well covered, right? So, but like what's next? What do we need? What has to happen for AI
To actually work and come to fruition and mature? And, which sectors will it affect and which subsectors could this potentially bring up? And then, we bring to the market like an AIPO, which is an AI infrastructure power and infrastructure ETF, right? So, it's just kind of like finding that little niche within the bigger pie to see if there's interest. And, that gathered a lot of interest, but yeah, it's just like really dissecting every single market theme and, news, what the retail investors are talking about, what institutions are talking about and, our own ideas and just trying to craft good products.
Well, let's get into one of the more recent launches, which is, an impactful fund. And I think for you guys, kudos to you and we want to talk through this, but let's get into ASD, which is the Defiance Autism Impact ETF. It's just been launched on June 2nd and this is the first ETF of its kind. At a very high level, what is this fund and what is the mission behind it?
Yeah. So, the birth of this ETF actually comes from, something that's very much close to all of our hearts here at Defiance. So, Matt Belsky and Gabrielle Azan Belsky have a son who is, on the autism spectrum and they've really spent his childhood supporting him and finding the right services to, help him grow, develop and thrive. And through that, they've, kind of met other people and seen how autism affects different families and what the financial constraints are, what the educational requirements are, the behavioral challenges are, the pharmaceutical challenges are and things like this. And it's really been something where, they've thought that through and wanted to create a fund that invests in the companies that just are
On the forefront of research and development in this space in hopes that, it helps the ecosystem grow, right? And that it has a good cause behind it. So, the fund actually donates 100% of the profits for a couple years to autism causes and then at least 50% after that. But, the broader picture here is 1 in 31 children are diagnosed with autism spectrum disorder. There are, specialized services, increased costs for behavioral therapies, and each of those children has a lifetime cost that's projected to be about $3 million per child. And so, it's a very challenging type of mission to work with this. And so, when we think about the companies in the ETF itself and like how this kind of ties together,
We look at companies that are working on this, right? So, whether it's drug development, genetic testing, whether it's diagnostic technologies, whether it's behavioral therapies, educational tools, digital health solutions, there are a lot of companies out there that do these things. And the index essentially researches this and looks at the entire value chain and creates this ASD index based on those companies that are involved with these things.
Yeah. So, you mentioned just, this is kind of touch Matt personally, and he's not on the show today. So, I don't know, how much we want to get into this, but how much do you think, Matt's lived experience like shapes this fund? it seems like it's purely index driven, but the philanthropic piece is probably has a lot to do with Matt's personal experience.
The philanthropic piece is 100% based on Matt's personal experience and the experiences that, we've all been exposed to with other families that are, either know someone, and if you talked to just about anyone, they'll say, my cousin, my nephew, my so-and-so, my friend's son is struggling with autism. So, this is just a very prevalent issue. But yes, very much the philanthropic aspect of it is 100% to, to really leave a mark and do something good in this world and advance autism research and hopefully autism cures. And yes, it's, the point about it being index based, right? We also want a good product. And if you think about what the autism ETF is, it's, again, it's a disease that impacts one in 31 people. This is a massive population
And companies that come up with the different technologies and hopefully cures and testings are going to benefit. And in that case, it could potentially be a good investment for people to hold on to if they're looking for biotech, healthcare, rare disease, things like this. The other thing I'll say about that is most institutions, like especially endowments and groups that we've talked to, really, really want to have some part of their portfolio and allocation dedicated to products for a cause. And so, there's certainly room for this in a portfolio
Allocation. Yeah. So, you touched on this slightly there, but, there are no FDA-approved medications for kind of the core symptoms of autism at this time. So, the full ecosystem is touching pharma, it's touching diagnostics, it's touching, behavioral therapy, education, even assistive technology. So, can you walk us through kind of the three core segments you're going to see
Inside of this fund? Sure. I think I can give you something. I can talk about some segments and also give you some examples, but it's going to be, drug development, genetic testing, diagnostic tech, behavioral therapies, educational tools, assisted technologies. Just to give you some examples, though, it's like Bright Spring. They do behavioral health and developmental disability. It's LifeStance. They do mental health and behavioral care utilized by individuals with autism. Shred and Pearson, educational platforms, Revity is diagnostics and genetic testing. But there are all sorts of pre-IPO companies also working on cures for autism. there's a company called, Yamo, for example, that is one of the, biotech companies out there that has a really good medical solution for children with autism that apparently, doesn't have side
Effects and helps improve quality of life. And there are going to be other companies like theirs, whether it's in the educational space and coming up with different ways to provide education, and behavioral services to children or to their parents. And I think that this is a nascent space. And if we just think about where the world is going with AI and, the future of biotech and pharma and how, even that aspect of it could improve over time, I just think that these are opportunities to get in, like at the very beginning, while these companies are just on the edge of breaking through with different solutions.
Yeah. So we, we touched on the philanthropic piece, like super briefly, but it is, it's genuinely important and it's a, it's a massive differentiator for this product. So Defiance is donating a hundred percent of net advisory profits during the first two years, and then no less than 50% thereafter to autism causes. So can you kind of talk about how that came together and, what organizations you see, these donations will support? Yeah. so again, I think a lot of ETFs are
Created because there's a popular trend as we talked about before, but this was really created because autism affects real families every single day. And the experiences that these families have with raising profoundly autistic children are essentially, harrowing. And I think that with the personal connection and the philanthropic donation here, there's just a level of authenticity, let's, let's say with this fund. It's something we really believe in and we'll hold true to our word and donate to different autism organizations. in terms of who we'll donate to, that, that is something that could potentially change over time, right? We want to make sure that we're working with different charities and organizations that are doing the things that we believe in. And so, when the time is appropriate, we'll kind of disclose who those, who and what those,
Organizations might be, but, just think of the most popular ones. We're certainly having conversations with them. Autism speaks and such. Yeah. Well, I genuinely hope that
This fund has as much success as your other funds and we can help propel that space forward and get families and people to help and the innovation that they need. And so with that, we are going to drastically shift gears away from this fund to, um, a, June 12th, maybe is a massive day. Um, SpaceX is slated to go public 1.75 trillion valuation, which would be the largest IPO in history. And you guys are launching SPCU, which is a two X long space S space X ETF the same day. Can you walk us through what this is going to offer to investors? Yeah. So, um, the,
The ETFs it's, it's, it's to be determined, um, in terms of the launch date in terms of, um, that, when it'll come out into the market, but, certainly after SpaceX IPOs. Um, so I would say that next week you'll see all of these ETFs trading is, is the most likely story, but we just think that, SpaceX has transformed, um, the, the buzz of SpaceX is, is just transforming the market, but the company itself has transformed space by basically reducing launch costs and increasing frequency. You have Starlink and the Starlink network, which has recurring revenues. You have these contracts with Google that bring in billions of dollars, but I think this is, this is just something where space is becoming a commercial industry.
It's going to be part of a huge ecosystem. Um, you're going to have everything from rockets, actual space, AI infrastructure, connectivity, communications, launch services, defense technology. Um, you're going to have, government investment in this particular space and not to mention that it's an Elon Musk company and it's, the next, next gen of, of Tesla. Right. And there was kind of so much excitement about that. And that, that took on many, many faces and shapes in terms of the different pillars that bring revenues. But, um, we're so excited to bring products into the market. There will be several that hold SpaceX, the SPCU will be the two X levered SpaceX ETF, but, um, we have a handful of others as well. Like XOVL actually
Has exposure to SpaceX already. Um, some of the thematic funds have built into the index methodology that they, could hold space and satellite types of names. So lots of excitement to come in, in the next week or two. And I think you'll see, um, a good amount of access and tools available for investors through, through SpaceX. Yeah. And that's what I was going to say. Like, there's really
Going to be no shortage of ways to get SpaceX exposure on day one. And the single stock two X from defiance and pro shares, a wave of buying, from index funds, space themes, ETFs, right? So why does defiance want to be in this category? And how do you think you're, maybe positioned a little bit differently than the rest? I think we have a great moat, right? We're,
We're going to have a two X long product, a two X short product. We have a basket of space, space names like, um, SPCL. We have, um, thematic one beta funds that hold it. We have other lever ETFs that are related to space. We've already put a lot of ETFs out there. you can see our, um, some of our two X single names like rocket labs is one of them. So I think that we've already been in space. We're one of the ETF companies that's known for our space exposure. And if you look at some of the other, even related stories, like you can look at a Jedi, which has, drones and satellite, the future of military warfare space is a huge,
It's a huge part of that, um, theme I think in general. And so I just think that it's been very much in line with our brand. It's something that we've been working on all along. And so, hopefully the market recognizes us for that. Yeah. And so like the space is con the space
Economy has gone from like niche theme to like mainstream, like rather quickly, I was just talking to, uh, Tema ETFs. They launched the NASA ETF gathered a hundred million in like a week. Yes. Uh, UFO crossed a billion. What's driving, what do you think is driving that demand from
Investors right now? Yeah. UFO X also crossed a billion too. Um, that's that one's ours, but yeah, I just think that investors are very much engaged in, where the puck is going for technology. Um, this was a word that a lot of people were using years ago and it's kind of died down because AI is the new buzzword, but, um, the fourth industrial revolution is, is, is here. We're living in it. Right. And with the growth of AI, quantum computing, super computing, um, if you think about, what is kind of needed for that and what grows from that, it's, it's connectivity, it's communications, it's moving data, it's, finding different ways to, to, to grow and support AI. And I think that space is just a natural, um, kind of
Cousin to all of these different themes. And so it's no surprise that investors are excited about it. But again, I think it's hard to argue that a big part of it isn't that, it's an Elon Musk company, right? I think there's just also just some buzz around Elon Musk and space. I think the two
Sometimes feel like they go hand in hand. Yeah, I can definitely see that. So we talked, um, we talked earlier about, the prolific growth of defiance. And so you've had launches in autism and drones and single stock letter plays, like what's the broader vision as we head into the back half of 2026. Do you think we're going to see more from defiance?
Oh, for sure. Um, we have been launching products almost weekly at this stage and you'll, you'll see a mix of things. You'll see new thematic products that represent, untouched subsectors are some of the major themes we've discussed today. So far, um, you will see more single name leverage funds coming out from defiance. We have, um, all sorts of innovative and creative filings that, that we have out there. And I think what you'll see from us is, is more disruption, more innovation. And I think you'll, you'll see us hopefully winning on bringing some new, um, disruptive and exciting themes to the market that investors want to trade.
So Sylvia, as we think about maybe the last 24 months, defiance is, is ballooned, personally for you, how's your life changed, I guess. And what's the company, what's the company look like today compared to 24 months ago?
Yeah, great question. So, um, as you can imagine, we're all a whole lot busier, right. And, and there's a lot of excitement that has come with that. And, I'll say just like on a personal note, like we're, we're super grateful, right? we, we started in 2018. It took a really long time to get to the point where we were able to put this many products into the market and see, some of the success that we have seen in the products that we put out there. It's just, a matter of time and, and, introducing yourself to the markets and, and, people kind of trusting in what you're building and doing. And so we've been so lucky to
Have the best supportive investors and, and, people cheering us on, on the sidelines. That's been just awesome. And we're grateful for it, but the company has grown, right? We're, we're no longer, just to start up, right? We have a larger team. Um, we have a great and brilliant team that supports all of the efforts and things that we do. Um, we're all very much, ambitious and passionate about what we do and the, as long as the good ideas keep on coming and we have the speed to get them to market and investors want to trade them. I think you'll just see continued growth from us.
Was that just curious when you're sitting around the table with a small team in 2018, was the idea always to get to a point where you guys are launching a product every week, or is that almost like a pivot or, uh, a business decision that happened another time after you started having success in some of these spaces? And it's like, Hey, let's just, let's just keep
Launching product. Uh, well, there's, there's obviously always a chicken and egg. You need, you need, balance sheet and growth to, to justify launching additional products. But yeah, we always, we had always planned to, to grow and to, to put products into the market and, um, to get our good ideas out there as fast and as often as we can. Right. So we're certainly very thoughtful in what we're putting into the market and everything that you see us launching and filing for is something that we very much believe in. And, not every ETF that's filed for ends up getting launched. So we're certainly selective, but, um, we, we have very high conviction in the things that we put out into the market.
Well, Sylvia, I always enjoy my time with you. Um, before I can, before I let you go, where can people learn all about defiance, get information on ASD and all of your ETFs?
Uh, that's defiance ETFs.com. And thank you, Brad, for having me.
All right. We'll talk soon. Thanks. Thank you.
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